The E-Z 96 Vacuum manifold is designed for DNA/RNA sample preparation with E-Z 96 DNA/RNA Plates. The chamber can be used either as a simple dump for waste filtrate or as a receptacle for a standard 96-well microtiter plate (collection plate). The upper plate has a machined recess that fits our filter plate and contains a custom gasket as well. The top plate has locating holes which correspond directly to the locating pins in the bottom plate for easy alignment and stability.