• Predicted molecular weight: 31.0 kDa
• No endotoxins, TAGS, and carrier-free
• Naturally folded and post-translationally modified

IBI recombinant proteins are expressed inPichia pastoris(yeast) system which provides many advantages overE. colisystems. Yeast systems promote proper protein folding and post-translational modifications for greater bio-activity. The recombinant proteins are endotoxin free and are purified without HIS-TAGS or any other TAG. IBI’s yeast expression system has proven to produce more active proteins that more closely resemble their host form.

B7-H2, also known as CD275, is a member of the B7 family. Mouse B7-H2 is expressed by antigen presenting cells including B cells, monocytes/macrophages and dendritic cells. It binds to the ICOS molecule. The interaction of ICOS/B7-H2 plays an important role in the T cell co-stimulation pathway.

The recombinant B7-H2 mouse protein has a predicted molecular weight of 31.0 kDa.

All IBI recombinant proteins are lyophilized and shipped at room temperature without carrier protein. Proteins can be reconstituted in sterile PBS with at least 0.1% of carrier protein such as BSA or cell assay media.

The B7-H2 mouse protein can be used in cell culture, as a B7-H2 ELISA Standard, and as a Western Blot Control.

Country of Origin: USA.