- Predicted molecular weight: 16.2 kDa
- No endotoxins, TAGS, and carrier-free
- Naturally folded and post-translationally modified
IBI recombinant proteins are expressed inPichia pastoris(yeast) system which provides many advantages overE. colisystems. Yeast systems promote proper protein folding and post-translational modifications for greater bio-activity. The recombinant proteins are endotoxin free and are purified without HIS-TAGS or any other TAG. IBI’s yeast expression system has proven to produce more active proteins that more closely resemble their host form.
Fibroblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGF family members are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. There are currently 24 members of the FGF family. FGF basic (FGF2)and FGF acidic (FGF1) are multipotential factors that stimulate and support proliferation, migration and differentiation.
The recombinant mouse protein FGF basic has a predicted molecular weight of 16.2 kDa.
All IBI recombinant proteins are lyophilized and shipped at room temperature without carrier protein. Proteins can be reconstituted in sterile PBS with at least 0.1% of carrier protein such as BSA or cell assay media.
The FGF basic mouse protein can be used in cell culture, as a FGF basic ELISA Standard, and as a Western Blot Control.
Country of Origin: USA