For enzyme digestion during DNA and RNA preparation.
Both OB Protease and Proteinase K offer broad substrate specificity with high activity for a wide range of salts, denaturant and detergent, pH, and temperature conditions. Proteinase K is a subtilisin-type protease isolated from the saprophytic fungus Tritirachiumalbum and is particularly suitable for short digestion times. It possesses a high specific activity which remains stable over a wide range of temperatures and pH values with substantially increased activity at higher temperature. OB Protease is a serine protease isolated froma recombinant Bacillus strain and is an economical alternative to Proteinase K for isolation of native DNA and RNA from a variety of sources. OB Protease is completely free of DNase and RNase activities.